Stuart Martin
Primary Investigator, Professor
ssmartin@som.umaryland.edu
https://www.medschool.umaryland.edu/profiles/Martin-Stuart/
Research
For the past 30 years, Dr. Martin has focused his research on the cell biology of metastatic tumor recurrence, unifying training in chemotherapy resistance, cytoskeletal signal transduction, apoptotic resistance and mouse breast tumor models. His lab discovered that circulating breast tumor cells produce unique extensions of the plasma membrane that were termed, microtentacles. These microtentacles promote tumor cell aggregation and reattachment to vascular endothelial layers, increasing the survival of circulating tumor cells in distant tissues. His group focuses on how cytoskeletal mechanics can influence breast cancer metastasis and clarifying how current chemotherapies that are aimed at cell division might actually increase metastatic risk. Research in his lab has been continuously supported by NIH for more than 15 years. He has served as mentor for 10 Ph.D. graduate students and 4 post doc fellows and has published more than 85 peer-reviewed research articles.
Accolades
- Endowed Professorship
- Drs. Angela and Harry Brodie Professor of Translational Cancer Research
- Departments of Pharmacology and Physiology
- Co-director, Hormone-Related Cancers (HRC) Group
- Chair, SOM Appointments Promotion and Tenure (APT) Committee
Education
- B.S. in Biology
- University of Virginia
- Ph.D. in Biomedical Sciences
- University of California, San Diego
- Post-doctoral Fellowship in Tumor Biology – Apoptosis
- Harvard University
Hobbies
Sailing, rock climbing, and spending time with family.
Martin Laboratory 